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Industrial filter cloth, filter mesh usage - vertical filter press filter cloth selection - making medicine, refining ibuprofen
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Detailed Description
- Industrial filter cloth and filter mesh usage - Vertical plate filter press filter cloth selection - Ibuprofen production for pharmaceutical extraction
Xiamen Citius Industrial Filter Cloth On-site Operating Case Pictures:
Filter type: Vertical plate filter press
Application industry: Pharmaceutical production
Material description: Ibuprofen
Application of industrial filter cloth and filter mesh in vertical plate filter presses for ibuprofen extraction
Introduction
Ibuprofen, as a widely used nonsteroidal anti-inflammatory drug ( NSAID ), its purity and quality during production directly affect its efficacy and safety. In industrial production, the extraction of ibuprofen involves multiple complex solid-liquid separation steps, and the vertical plate filter press, as a highly efficient filtration device, plays a key role in the purification process. This article focuses on the application of industrial filter cloth and filter mesh in vertical plate filter presses, especially the technical advantages and practical challenges in the ibuprofen extraction process.
Brief description of vertical plate filter press and its working principle
A vertical plate filter press is a device that uses pressure to achieve solid-liquid separation. It mainly consists of a filter chamber, filter plates, filter cloth (or filter mesh), and a hydraulic system. The material slurry is fed into the filter chamber, the liquid is filtered out through the filter cloth, and the solid is retained to form a filter cake. The filter cloth not only acts as a filtration medium but also ensures the uniform formation and effective dehydration of the filter cake. Compared with horizontal plate filter presses, vertical plate filter presses have a compact structure and flexible operation, making them particularly suitable for the strict cleanliness and space requirements of pharmaceutical production.
The key role of industrial filter cloth and filter mesh
In vertical plate filter presses, industrial filter cloth and filter mesh are the core components that ensure filtration effectiveness. Their main functions include:
- High-efficiency filtration : The filter cloth has a fine pore size, which can retain fine solid impurities in the drug to ensure liquid purity.
- Corrosion and abrasion resistance : The chemical solvents and drug reactants in the pharmaceutical process have high requirements for the filter cloth material. Industrial filter cloth must have good chemical stability and mechanical strength.
- Good filter cake release : The filter cloth must ensure that the filter cake can be easily removed when the filter press is opened to avoid residue and cross-contamination.
- Reusability : In pharmaceutical production, the service life of the filter cloth affects production costs and equipment operating efficiency.
Filter mesh is usually used as a support layer or pre-filtration medium for filter cloth to improve the mechanical strength and filtration uniformity of the filter cloth.
Filtration stage in ibuprofen extraction process
The industrial synthesis of ibuprofen mainly includes esterification, hydrogenation, hydrolysis, and crystallization steps. The product usually contains impurities and unreacted substances, which need to be purified through multiple filtrations and washings. Among them, the vertical plate filter press is responsible for solid-liquid separation. The separated filter cake contains undissolved impurities or intermediates, and the filtrate is the basis for subsequent refining.
The quality of the filtration stage directly determines the purity and particle uniformity of ibuprofen. Suitable industrial filter cloth not only increases the filtration speed and reduces energy consumption but also effectively reduces the moisture content of the filter cake and improves drying efficiency.
Filter cloth materials and performance requirements suitable for ibuprofen extraction
The pharmaceutical industry has extremely high hygiene and performance standards for filtration media. Filter cloths for ibuprofen extraction usually require:
- Chemical stability : The filter cloth must be resistant to corrosion by acids, alkalis, and solvents. Commonly used high-performance synthetic fibers include polyester ( PET ), polyamide ( PA ) etc.
- Fine and uniform pore structure : Ensure filtration retention effect, the pore size is generally controlled in the micrometer range.
- High mechanical strength : Able to withstand high-pressure filtration and repeated cleaning and disinfection.
- Good filter cake release : Helps the filter cake to fall off completely, avoiding product waste.
- Compliant with GMP and pharmaceutical hygiene standards : Filter cloth and filter mesh materials must meet pharmaceutical-grade requirements and release no harmful impurities.
Modern pharmaceutical filter cloths often use coating technology or composite structure design to improve corrosion resistance and filtration efficiency.
Technical difficulties and solutions in application
1. Filter cloth life and maintenance
Frequent filtration and cleaning make the filter cloth prone to wear and clogging. Selecting high-strength fibers and a scientific filter cloth structural design can extend the service life. Using automatic cleaning technology and filter cloth replacement warning systems is also an effective measure to improve equipment operating efficiency.
2. Filter cake uniformity and detachment issues
Non-uniform filter cake will affect the subsequent drying and purification effects. Reasonably designing the filter cloth surface structure and selecting a filter cloth suitable for the characteristics of drug particles can effectively avoid filter cake breakage and clogging.
3. Balance between filtration efficiency and production capacity
The smaller the filter cloth pore size, the better the filtration effect, but the lower the flow rate and the lower the production capacity. By optimizing the filter cloth material and equipment pressure control, the best balance between filtration speed and accuracy can be achieved.
4. Compliance with pharmaceutical safety regulations
Production filter cloths must be pollution-free and easy to disinfect. At present, most of them comply with FDA 、 EU Materials meeting pharmaceutical standards, combined with rigorous production and testing processes.
Conclusion
Industrial filter cloths and filter screens are crucial in the vertical filter press for the refining process of ibuprofen. They not only ensure the efficiency and quality of solid-liquid separation, but also directly affect the purity and production cost of the drug. With the continuous advancement of pharmaceutical processes, the performance requirements for filter cloths are also increasing. In the future, combining new material technologies and intelligent manufacturing, the design and application of filter cloths will be more precise and efficient, providing a solid guarantee for the high-quality production of ibuprofen and other pharmaceutical products.
📞 For technical support or sample testing services, please contact Xiamen Citius (Xiamen Citius) ：
- Email: wyl@citius-filter.com
- WhatsApp: +86-13950107241
- Official Website : www.citius-filter.com
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